METHOD OF SYNTHESIS OF ACETYLENE HYDROXYACID METHYL ESTERS

摘要

FIELD: organic chemistry, derivatives of carboxylic acids. SUBSTANCE: synthesis of acetylene hydroxyacid esters is carried out by methoxycarbonylation of corresponding acetylenic alcohols in the presence of the following catalytic system: PdCl₂/CuCl₂ or CH₃COONa at molar ratio CuCl₂ or CH₃COONa, alcohol and PdCl₂ = (3-4.3): 1: (0.2-0.43) in the medium of methanol at 12-16 C. EFFECT: enhanced yield of the end products due to the change of process regime.