Method for obtaining highly pure, virus-inactivated factor VIII by means of anion exchange chromatography

摘要

PCT No. PCT/EP93/00114 Sec. 371 Date Aug. 29, 1994 Sec. 102(e) Date Aug. 29, 1994 PCT Filed Jan. 20, 1993 PCT Pub. No. WO93/15105 PCT Pub. Date Aug. 5, 1993Described is an economical process for the recovery of factor VIII from blood plasma or cryoprecipitate. In the process, anion exchanger chromatography is conducted using a separating material based on carriers containing hydroxyl groups, the surfaces of which carriers have been coated with covalently boded polymers. The polymers contain repeating units represented by formula (I). IMAGE