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daitosaijin and its production manner

机译:大斋斋金及其生产方式

摘要

NEW MATERIAL:A daitocidins expressed by formula I (R is 12-14C alkyl; X is Val or Ilambdaeu). EXAMPLE:A compound expressed by formula II. USE:A gastric inhibitory agent, gastric ulcer preventing and treating agent, antiphlogistics, platelet aggregation inhibiting agent, antiallergic agent, etc., having H+,K+-adenosine triphosphatase inhibiting action and phospholipase A2 inhibiting action. PREPARATION:For example, Bacillus espi Q-55 (FERM P-9299) separated from the soil of the Minamidaito island is cultivated in a suitable culture medium under aerobic conditions, preferably by shake culture or aerobic culture in preferred conditions at 33-40 deg.C and pH 5.5-7.0 for 3-5 days and the aimed Daitocidins are collected from the cultivation product.
机译:新材料:由式I表示的甜菊糖苷(R为12-14C烷基; X为Val或Ilambdaeu)。实施例:由式II表示的化合物。用途:具有H +,K +-腺苷三磷酸酶抑制作用和磷脂酶A2抑制作用的胃抑制剂,胃溃疡预防和治疗剂,消炎药,血小板凝集抑制剂,抗过敏剂等。制备:例如,从南大东岛土壤中分离的芽孢杆菌Q-55(FERM P-9299)在有氧条件下的合适培养基中培养,最好在优选的条件下于33-40度通过摇动培养或有氧培养C.和pH 5.5-7.0持续3-5天,并从培养产物中收集目标的菊苣素。

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