NOVEL SUBSTITUTED THIAZOLYL DERIVATIVES AND SUBSTITUTED PYRIDINYL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND ANTI-ALLERGIC PREPARATIONS BASED THEREON

摘要

The novel substituted thiazolyl derivatives and substituted pyridinyl derivatives of the general formula I and their pharmaceutically acceptable acid addition salts and stereochemically isomeric forms, where -A.sup.1.n. Represents a divalent radical of formula (a-1 to (a-7) -CH = CH-CH = CH- (a-1), -CH = CH-CH = N- (and -5), -N = CH-CH = CH- (a-2), -N = CH-N = CH- (a-6), -CH = N-CH = CH- (a-3), - CH = N-CH = N- (a-7), -CH = CH-N = CH- (a-4), B represents the radical NR.sup.1, CH.sub.2, O, S, SO or SO2, wherein R5 is a hydrogen atom of C1-4alkyl, R is a radical of formula (b-1) or ( b-2), wherein D is C.sub.1-4 .alkanediyl; C 1-6 alkenyl, optionally substituted with aryl; C 1-6 alkyl; C 1-6 alkyl; C 1 -C 6 -alkoxycarbonyl; arylcarbonyl; arylC 1-6 -alkoxycarbonyl; or a radical of formula (c-1) to (c-4) -Alk-R. sup.3 à