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A method for preparing a stable, injectable beta-carotene solubilizate

机译:一种制备稳定的可注射的β-胡萝卜素增溶剂的方法

摘要

Method for the continuous preparation of beta -carotene solubilisates by brief heating of beta -carotene together with an emulsifier until solution takes place, rapid cooling of the homogeneous solution to below 100 DEG C by addition of water and subsequent adjustment of the required final concentrations of beta -carotene, which is characterised in that a suspension, which has been preheated to 20 to 80 DEG C, of 1 to 40% by weight beta -carotene in an emulsifier is pumped through a heating coil located in a heat-transfer oil, where the temperature in the solubilisation mixture is 120 to 180 DEG C and the residence time is 10 to 300 seconds, and the homogeneous solution is turbulently mixed in a mixing chamber with such quantities of water at 10 to 80 DEG C that a solubilisate containing 0.5 to 6% by weight beta -carotene is produced and is, where appropriate, further diluted to the required final concentration.
机译:通过短暂加热β-胡萝卜素和乳化剂直至溶液发生,连续制备β-胡萝卜素可溶物的方法,通过加水将均相溶液快速冷却至100℃以下,随后调节所需的最终浓度β-胡萝卜素,其特征在于将乳化剂中已预热至20至80℃的1至40重量%β-胡萝卜素的悬浮液泵送至位于传热油中的加热盘管中,其中增溶混合物中的温度为120至180℃,停留时间为10至300秒,并且均质溶液在混合室中与10至80℃的如此量的水湍流混合,使得增溶剂含有0.5产生了β-胡萝卜素至6重量%的β-胡萝卜素,并在适当的情况下进一步稀释至所需的最终浓度。

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