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Preparation of polynucleotides using purified polynucleotide phosporylase
Preparation of polynucleotides using purified polynucleotide phosporylase
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机译:使用纯化的多核苷酸磷酸化酶制备多核苷酸
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摘要
This invention relates to a process of preparation of nucleotide polymers wherein a lysate of a bacterial culture is passed successively through three columns (ion exchange resin, hydrophobic resin and molecular sieve), whereby there is obtained a substantially pure polynucleotidephosphorylase solution. Polymerization of this agent leads to non toxic and non pyrogen products. This invention relates also to products thus obtained and to therapeutic compositions containing the same.
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