4-4-4-4-2-(2 4-Difluorophenyl)-2-(1h-azolylmethyl)-1 3-dioxolan-4-yl metholxy phenyl -1-piperazinyl phenyl triazolones and imidazolones their preparation and antifungal compositions containing them

摘要

4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4 -yl]methoxy]pheny l ]-1-piperazinyl]phenyl]triazolones and imidazolones of formula CHEM wherein Q is CH or N; Y is a radical of formula CHEM R1 is C5-7cycloalkyl or mono-, di-, tri-, tetra- or pentahaloC1-4alkyl; and R2 is C1-6alkyl, C5-7cycloalkyl or mono-, di-, tri-, tetra- or pentahaloC1-4alkyl, the acid addition salts and stereoisomeric forms thereof; said compounds having antifungal properties. Pharmaceutical compositions containing such compounds as an active ingredient; methods of preparing said compounds and pharmaceutical compositions.