Pharmaceutical formulations containing melphalan or melphalan hydrochloride, as well as melphalan and melphalan hydro-chloride and processes for preparing them

摘要

The present invention relates to a new two-component pharmaceutical formulation of melphalan in which the two components comprise a) freeze-dried mephalan hydrochloride and b) a solvent-diluent comprising a citrate, propylene glycol and ethanol. Substantially pure melphalan, substantially pure melphalan hydrochloride and methods for preparing them are also described.