首页> 外国专利> use of farnesyl protein transferaseinhibitoren in the manufacture of a product for blocking of ras oncogenen induced neoplastic transformations of cells.

use of farnesyl protein transferaseinhibitoren in the manufacture of a product for blocking of ras oncogenen induced neoplastic transformations of cells.

机译:法呢基蛋白转移酶抑制剂的用途在制造用于阻断ras致癌基因诱导的细胞肿瘤转化的产品中。

摘要

A method is provided by blocking or preventing the prenylation of CAAX box containing proteins including ras oncogene products thereby preventing and/or treating ras-related tumors which includes the step of administering a therapeutically effective amount of a protein-prenyl transferase inhibitor.
机译:提供了一种通过阻断或阻止含有CAAX盒的蛋白质的异戊二烯基化的方法,该蛋白质包括ras癌基因产物,从而预防和/或治疗ras相关肿瘤,该方法包括给予治疗有效量的蛋白质-异戊二烯基转移酶抑制剂的步骤。

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