Process for the synthesis of 3- (2-dimethylamino) ethyl) -N-methyl-1H-indole-5-methanesulfonamide.

摘要

PROCEDURE FOR SYNTHESIS 3 - [(2-dimethylamino) ethyl-1-N-methyl-1-5-methanesulfonamide IINDOL. THE PURPOSE of the invention to obtain a hydrazone INTERMEDIATE starting with 4-amino-N-METILBENCENOMETANOSULFONAMIDA and 2- (3-dimethylaminopropyl) CIANOCETATO acetate, treating the reaction product with an acid in an alcoholic medium TO OBTAIN indole-2-carboxylic and effecting subsequent decarboxylation FOR THE 3 - [(2-dimethylamino) ethyl] -N-methyl-LH-INDOL-5METANOSULFONAMIDA, which is recrystallized AN ORGANIC sOLVENT II according to Scheme To address Y PREVENTING VASCULAR EXPANSION CRANEAL.