首页> 外国专利> gene fragments coding for the variable regions of an anti-HIV chimeric anti-HIV antibody expressed, antibodies using the same and process for their preparation.

gene fragments coding for the variable regions of an anti-HIV chimeric anti-HIV antibody expressed, antibodies using the same and process for their preparation.

机译:编码抗HIV嵌合抗HIV抗体的可变区的基因片段,使用该抗体的抗体及其制备方法。

摘要

HIV chimeric ARE - NEW antibodies to the virus (HIV) FOR THE IMMUNE anti-human chimeric, comprising a constant region derived from a monoclonal mouse gene fragments coding for the variable region CHAINS HYL of anti DESCRIBED eFFECTIVE FOR EXPRESSION OF ANTI - HIV CHIMERIC HIV neutralizing activity, INCORPORATED TRANSFORMER WHERE GENETIC said fragments, ANTI - HIV expressed from this and a process for their preparation. The anti - HIV Chimeric the present invention show activity Neutralizer ANTI - HIV and are useful in the diagnosis, treatment and prevention Immune Deficiency Syndrome (AIDS) caused by HIV WITHOUT SIDE EFFECTS AS Anaphylactic shock serum sickness.
机译:HIV嵌合体-用于免疫抗人嵌合体的新型病毒(HIV)抗体,包含一个恒定区,该恒定区衍生自编码可变区的单克隆小鼠基因片段,抗表达的链烷烃有效表达抗HIV嵌合体HIV中和活性,在基因组学所述的片段中,抗坏血酸的表达以及由此制备的抗-HIV及其制备方法。本发明的抗-HIV嵌合体显示出中和剂抗-HIV的活性,并且可用于诊断,治疗和预防由HIV引起的免疫缺陷综合症(AIDS),而没有副作用,如过敏性休克血清病。

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