首页> 外国专利> 1,3,8,10 tetrasubstituted derivatives of 4,5,6,7-tetrathiocino-(1,2-b:3,4-b')-diimidazolyl-2,9-dithio ne, their preparation and their use as antitumor agent

1,3,8,10 tetrasubstituted derivatives of 4,5,6,7-tetrathiocino-(1,2-b:3,4-b')-diimidazolyl-2,9-dithio ne, their preparation and their use as antitumor agent

机译:1,5,6,7-四硫代噻吩基-(1,2-b:3,4-b')-二咪唑基-2,9-二硫代萘的1,3,8,10四取代衍生物,其制备及用途抗肿瘤药

摘要

1,3,8,10 tetrasubstituted compounds of 4,5,6,7-tetrathiocino-(1,2-b:3,4-b')-diimidazolyl-2,9 dithione of formula (I), wherein R is selected from the class consisting of: C3-C5 linear or branched alkyl, benzyl, 2-thiophenyl-methyl. Therapeutical compositions having antitumor activity containing as the active principle at least one derivative of formula (I), wherein the R substituent is selected from the class consisting of C1-C5 linear or branched alkyl, phenyl, o-tolyl, benzyl, 2-thiophenylmethyl, in combination with suitable excipients and/or diluents.
机译:式(I)的4,5,6,7-四硫代-(1,2-b:3,4-b')-二咪唑基-2,9二硫酮的1,3,8,10四取代的化合物,其中R为选自:C3-C5直链或支链烷基,苄基,2-硫代苯基-甲基。具有抗肿瘤活性的治疗组合物,包含至少一种式(I)的衍生物作为活性成分,其中R取代基选自C1-C5直链或支链的烷基,苯基,邻甲苯基,苄基,2-硫代苯基甲基,与合适的赋形剂和/或稀释剂结合使用。

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