NOVEL PEPTIDE, AND ANTITHROMBOTIC AGENT, ANTICOAGULANT FOR EXTRACORPOREAL CIRCULATION, CELL FUSION INHIBITOR, CANCER METASTASIS INHIBITOR, PROTECTIVE FOR PLATELET PREPARATION FOR TRANSFUSION AND PACK OF PLATELET PREPARATION FOR TRANSFUSION

摘要

The invention provides a novel peptide derivative comprising RGD as the basic skeleton and having antithrombotic, anticoagulant and cell fusion inhibiting effects. The invention provides also an antithrombotic agent which is efficacious against thrombosis and thrombolus during or after thrombolytic therapy and which can prevent the recurrence of such diseases and myocardial infarction, and anticoagulant for extracorporeal circulation which can inhibit clotting as the principal cause of thrombus during extracorporeal circulation, a cell fusion inhibitor, a cancer metastasis inhibitor, and a protective for a platelet preparation for transfusion, each containing the above derivative as the active ingredient. The invention further provides a pack of a platelet preparation for transfusion containing the derivative.