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Use of beta-adrenergic agonists for treating loss of function of striated muscles

机译:β-肾上腺素能激动剂在治疗横纹肌功能丧失中的用途

摘要

This invention relates to novel therapeutic uses of beta-adrenergic agonists in humans and animals. The uses include increasing muscle growth and reducing fat uptake from dietary input, retarding or reversing atrophy of denervated muscle, alleviating or reversing the effects of various diseases (including cancer), modification of foetal and neonatal growth, and possible genetic modifications of the developing foetus.;The preferred beta-adrenergic agonist is clenbuterol.;Surprisingly, the beta-adrenergic agonist can be mixed with a beta-adrenergic antagonist to obviate or mitigate unwanted side-effects without excessively inhibiting the wanted novel effects.
机译:本发明涉及β-肾上腺素能激动剂在人和动物中的新的治疗用途。用途包括增加肌肉生长和减少饮食摄入的脂肪,延缓或逆转神经支配的肌肉萎缩,减轻或逆转各种疾病(包括癌症)的影响,改变胎儿和新生儿的生长以及发育中的胎儿的可能的遗传修饰;优选的β-肾上腺素能激动剂是克仑特罗。令人惊讶地,可以将β-肾上腺素能激动剂与β-肾上腺素能拮抗剂混合以消除或减轻不需要的副作用,而不会过度抑制所需的新作用。

著录项

  • 公开/公告号EP0662324A1

    专利类型

  • 公开/公告日1995-07-12

    原文格式PDF

  • 申请/专利权人 THE ROWETT RESEARCH INSTITUTE;

    申请/专利号EP19950101362

  • 发明设计人 MALTIN CHARLOTTE;

    申请日1988-09-12

  • 分类号A61K31/135;A61K31/275;A61K31/52;

  • 国家 EP

  • 入库时间 2022-08-22 04:12:43

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