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Process for the production of vaccine for prevention of Pasteurella haemolytica pneumonia in bovine
Process for the production of vaccine for prevention of Pasteurella haemolytica pneumonia in bovine
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机译:预防牛溶血性巴斯德氏菌肺炎的疫苗生产方法
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摘要
A serum-free vaccine effective against pneumonic pasteurellosis in cattle comprising a non-toxic leukotoxin specific for ruminant leukocytes is disclosed. The leukotoxin is prepared in a serum- free medium from a culture of Pasteurella haemolytica. The produced leukotoxin is harvested from the culture medium upon detecting a certain stage during the logarithmic phase of the cell growth to obtain the optimum concentration of produced cytotoxin in the serum-free medium. Cattle may be treated with the vaccine to develop anti-leukotoxic immunity to pneumonic pasterellosis.
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