Gene transfer into epithelial cells of pancreas and bile duct

摘要

The present invention relates to methods for selective somatic gene transfer into a patient's pancreatic or biliary epithelial cells. The methods of this invention comprise introducing the gene to be transferred, associated with an appropriate transfer vehicle, into the ductal system of either the pancreas or liver. More specifically, the invention relates to using these techniques to, treat genetic disease, such as cystic fibrosis, which are characterized by genetic defects in those epithelial cells. IMAGE