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A wide range of tumor suppressor genes and gene products and methods of tumor suppressor gene therapy

机译:多种抑癌基因和基因产物以及抑癌基因治疗方法

摘要

The present invention relates to a wide variety of tumor suppressor genes and proteins expressed by genes in appropriate host cells. The protein is a second in-frame AUG codon-initiated retinal subpopulation protein with a molecular weight of about 94 kD. The present invention relates to a method of treating mammals having a disease characterized by abnormal cell proliferation such as cancer or tumor cells. The treatment is carried out with p94RBExpression vector or p94RBAnd administering the protein into the host cell.
机译:本发明涉及多种肿瘤抑制基因和由基因在合适的宿主细胞中表达的蛋白质。该蛋白质是第二个框内AUG密码子引发的视网膜亚群蛋白质,分子量约为94 kD。本发明涉及一种治疗患有以异常细胞增殖为特征的疾病,例如癌细胞或肿瘤细胞的哺乳动物的方法。用p94 RB 表达载体或p94 RB 表达载体进行处理,然后将蛋白施用于宿主细胞。

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