Nuclear Transfer of Shiitake Mushroom and Ganoderma lucidum and Method for Producing the Same

摘要

The present invention relates to a method for producing a nuclear transfer of mycelia of mushrooms and gingival mycelium, which are bacterium strains showing mutual hydrolysis of hyphae with each other, and a nuclear transfer having improved pharmacological activity thus obtained. That is, the mycelia of mushroom and mushroom were reacted with cell wall degrading enzyme to produce respective protoplasts, the protoplasts of the mushroom were homogenized and centrifuged to separate the nuclei, the nucleus of the mushroom and the protoplasts of the myrrh Which comprises preparing a nuclear transfer product of a mushroom and a ginseng mushroom by reacting the same with a solution of the mushroom to produce a nuclear transfer product and suspending the nuclear transfer product in an osmotic pressure stabilizer, Nuclear transfer L4ClN12 or N39 of the hyphoxanthin-requiring mutant of Ganoderma lucidum is an excellent strain having improved pharmacological activity over parent strain.