Mixed composition of plant extract and domperidone that has a promoting effect on gastric emptying ability of domperidone and does not affect small intestine transport

摘要

The present invention relates to a mixed composition of plant extract and domperidone, which has a gastric excretion effect of domperidone and does not affect the small intestine transport, comprising at least one selected from domperidone, red pepper, spearmint, health, sine and cinnamon. Plant ingredients are extracted and added in a conventional manner with one or more solvents selected from water, lower alcohols or chlorinated hydrocarbons, mixed with conventionally acceptable pharmaceutically acceptable excipients and formulated in the form of conventional pharmaceutical formulations to be excreted in the stomach. It provides a pharmaceutical composition having a potency promoting effect.;The mixed composition of the domperidone and the plant extract of the present invention has a higher gastric emptying capacity compared to domperidone, and is a new composition that eliminates the side effects of inhibiting the small intestinal transport capacity when domeperidone alone is administered.