首页>
外国专利>
LACTAM DIPEPTIDES SHOWING INHIBITORY ACTION ON HUMAN LEUKOCYTE ELASTASE, INTERMEDIATE COMPOUNDS, METHOD OF SYNTHESIS, PHARMACEUTICAL COMPOSITION
LACTAM DIPEPTIDES SHOWING INHIBITORY ACTION ON HUMAN LEUKOCYTE ELASTASE, INTERMEDIATE COMPOUNDS, METHOD OF SYNTHESIS, PHARMACEUTICAL COMPOSITION
展开▼
机译:内酰胺二肽对人白细胞弹性蛋白酶,中间体化合物,合成方法,药物成分具有抑制作用
展开▼
页面导航
摘要
著录项
相似文献
摘要
FIELD: organic chemistry, chemistry of peptides. SUBSTANCE: new heterocyclic compounds, in part, 1-pyridylacetamide compounds that are inhibitors of human leukocyte elastase (elastase of human neutrophilic leukocytes). This inhibition of elastase can be useful tool in pharmacology, diagnostic and related investigations and for mammalian diseases treatment where elastase takes part. Invention involves also intermediate compounds that can be used for synthesis indicated heterocyclic compounds, method for synthesis of heterocyclic compounds, pharmaceutical compositions containing indicated heterocyclic compounds and methods of their application. EFFECT: improved method of synthesis of new lactam dipeptides.
展开▼