PREPARATION OF CHIRAL 3-(AMINOMETHYL)-5-METHYL-HEXANOIC ACID AND ANALOGUES; HEXANOIC ACID DERIVATIVES AND ANALOGUES; USE AS ANTISEIZURE AGENTS 3-METHYL HEXANOIC ACID DERIVATIVES

摘要

A compound of formula (I) wherein R1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R2 is hydrogen or methyl; and R3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are also disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are further disclosed.