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METHOD FOR ASSESSING RISK TO DEVELOP PSYCHOTIC DISEASE

机译:评估发展为心理疾病的风险的方法

摘要

A method for use in assessing whether a subject is likely to be at risk of developing a psychotic disorder, such as schizophrenia, bipolar altective disorder or unipolar depression, the method comprising testing for and detecting the presence or absence of DNA encoding the 10- and/or 12-repeat alleles of the VNTR on the hSERT gene in a biological sample obtained from said subject. The claimed invention also concerns a cell-line and a transgenic animal expressing the 10- and/or 12-repeat.
机译:一种用于评估受试者是否有可能患精神病的风险的方法,例如精神分裂症,双相性精神障碍或单相性抑郁症,该方法包括测试和检测是否存在编码10-和10-DNA的DNA。在从所述受试者获得的生物学样品中,hSERT基因上的VNTR的12个重复等位基因。所要求保护的发明还涉及表达10-和/或12-重复的细胞系和转基因动物。

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