A method for the production of 13c - marked compounds

摘要

A process for preparing a 13C-labelled compound which comprises reacting an alcohol 13C-labelled carbon source compound and a substrate in the presence of an enzyme system consisting of oxidase belonging to EC1 group and capable of converting the alcohol 13C-labelled carbon source compound to an aldehyde 13C-labelled carbon source compound, lyase belonging to EC4 group and capable of synthesizing a carbon-carbon bond and at least one of isomerases belonging to EC5 group and capable of isomerizing substrates to obtain a 13C-labelled compound specifically labelled with 13C in a specific carbon position.