The oxidation of heterocycles of the nitrogen oxides and n - heterocyclic compounds by this oxidation

摘要

It provides a process for the production of n - oxides aromatic heterocyclic by reacting a compound comprising an aromatic heterocyclic nitrogen atom and hydrogen peroxide in the presence of a catalyst of porphyrin manganese. The catalyst of porphyrin of manganese is substituted by an aromatic group at each position meso, the aromatic rings of the aromatic substituents being substituted by one or more groups attractors of electrons and / or containing a heteroatom, quaternary ammonium aromatic in the aromatic nucleus. Preferably, the catalyst of porphyrin of manganese is the chloride of tetrakis (2,6 - 3,4-dichlorophenyl) porphyrin of manganese, the chloride of tetrakis (2,6 - 3,4-dichlorophenyl - 4 - sulphonic acid) porphyrin of manganese, the chloride of tetrakis (4 - methylpyridinium) porphyrin of manganese or the chloride of tetrakis (pentafluorophenyl) porphyrin of manganese.