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Use of excitatory opioid receptor antagonists to prevent growth factor- induced hyperalgesia
Use of excitatory opioid receptor antagonists to prevent growth factor- induced hyperalgesia
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机译:使用兴奋性阿片受体拮抗剂预防生长因子引起的痛觉过敏
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摘要
This invention relates to a method of preventing hyperalgesia and other undesirable side-effects associated with the administration of growth factor, including nerve growth factor, utilizing an antagonist capable of inactivating excitatory opioid receptor-mediated functions on neurons in the nociceptive pathway. In addition, this invention relates to a composition comprising a growth factor and an antagonist capable of inactivating excitatory opioid receptor-mediated functions on neurons in the nociceptive pathway.
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