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Amphiphilic compounds derived from amino acids or peptides, their methods of synthesis and their application as drug delivery systems
Amphiphilic compounds derived from amino acids or peptides, their methods of synthesis and their application as drug delivery systems
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机译:衍生自氨基酸或肽的两亲化合物,其合成方法及其在药物递送系统中的应用
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摘要
Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.
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