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Combinations for the treatment of congestive heart failure, and insulin-like growth factors and growth hormone
Combinations for the treatment of congestive heart failure, and insulin-like growth factors and growth hormone
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机译:组合治疗充血性心力衰竭,胰岛素样生长因子和生长激素
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摘要
Methods of enhancing myocardial contractility and cardiac performance in a mammal with congestive heart failure are disclosed. In a first method a mammal with congestive heart failure is treated by administering to the mammal an effective amount of a combination of growth hormone (GH) and insulin-like growth factor (IGF-I). A second method comprises administering to the mammal an effective amount of a combination of GH and IGF-I in the presence of an ACE inhibitor. This method results in enhancement of myocardial contractility and cardiac performance above the level achieved with ACE inhibition alone. Preferably the mammal is a human.
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