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AUXILIARY AGENT FOR DIRECT TABLETING, TABLET COMPRISING THE SAME AUXILIARY AGENT AND PRODUCTION OF TABLET
AUXILIARY AGENT FOR DIRECT TABLETING, TABLET COMPRISING THE SAME AUXILIARY AGENT AND PRODUCTION OF TABLET
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机译:直接制片的辅助剂,包括相同的辅助剂和片剂生产的片剂
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摘要
PROBLEM TO BE SOLVED: To prepare an auxiliary agent for direct tableting, capable of rapidly disintegrating at a low dusting ratio and having a high uptake capacity for a hardly tableted ingredient in spite of a good fluidity and a good binding power possessed thereby in order to form a tablet having a moderate hardness. SOLUTION: This auxiliary agent for direct tableting (i.e., the one without containing an active substance) comprises the following mixture: (A) 75-98wt.%, preferably 89-93wt.% powdery cellulose suitable for tableting with (B) 1-15wt.%, preferably 2-6wt.% soluble polyvinylpyrrolidone and (C) 0.5-10wt.%, preferably 2-5wt.% insoluble polyvinylpyrrolidone.
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