首页> 外国专利> Esters and amides of 1,4 - piperidine disustituida acceptable acids, their salts from the Physiological Point of viewA procedure for supreparacion and Pharmaceutical preparations which contain the.

Esters and amides of 1,4 - piperidine disustituida acceptable acids, their salts from the Physiological Point of viewA procedure for supreparacion and Pharmaceutical preparations which contain the.

机译:1,4-哌啶二氮杂可接受的酸的酯和酰胺,从生理学的角度看,它们的盐是用于制备超程的方法和包含其的药物制剂。

摘要

A new active agent ester and amide for 1.4-nitrous oxide (1.4-n 2O 2) of the general formula (I) 5-htm4 were introduced,Where: A is a formula (a), in which R1 is alcoxi, R2 is halo or heterocycle B of various formulas, cy D; R3 is h or halo; R4 is h or tar; R5 is h or alcoxi; R6 is h or tar; X is oxygen or NH; and represents a group of R7 or nhr7 formulas, where R7 is c1-3 tar, arilo or aralquilo; R is hydrogen, phenyl or hydroxy, Phenyl, methylthioyl, 3-indolea, methylcarbides or carbamates; and acid additive salts containing pharmaceutically acceptable acids. The preparation procedures of these compounds are also introduced,Pharmaceutical preparations containing these substances and their use in the treatment of patients with heart rhythm disorders, intestinal motor disorders, anxiety, depression, psychosis, cognitive disorders, motor disorders, alcoholism and immigration.
机译:介绍了一种新的通式(Ⅰ)5-htm4的1.4-一氧化二氮(1.4-n 2O 2)的活性剂酯和酰胺,其中:A为式(a),其中R1为醇氧,R2为各种式的卤素或杂环B,cy D; R3是h或卤素; R4是h或tar; R5是h或alcoxi; R6是h或tar; X是氧或NH;并且代表一组R 7或nhr 7式,其中R 7为c1-3 tar,arilo或alalquilo; R是氢,苯基或羟基,苯基,甲硫基,3-吲哚,甲基碳化物或氨基甲酸酯;含有药学上可接受的酸的酸加成盐。还介绍了这些化合物的制备方法,含有这些物质的药物制剂及其在治疗心律失常,肠道运动障碍,焦虑,抑郁,精神病,认知障碍,运动障碍,酒精中毒和移民中的用途。

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