METHOD FOR EVALUATING THE EXTENT OF A LITHOGENESIS PROCESS INTENSITY AND FOR DETERMINING THE COMPOSITION OF LITHOGENIC URATE SALTS IN UROLITHIASIS

摘要

The present method for evaluating the extent of alithogenesis process intensity and for determining thecomposition of lithogenic urate salts in urolithiasis residesin adding an aqueous protein solution to a urine sample in aratio of 9:1, 7:1 or 5:1, respectively; applying the mixturethus-prepared as a drop onto a smooth surface for drying forat least 24 hours; determining the nature of crystallizationof urate salts in the marginal zone of the urine sample, thepresence of separate, singly occurring crystals,conglomerates of crystals and a complete crystallization of thismarginal zone being indicative, respectively, of a weak,moderate or a highly pronounced extent of a lithogenesisprocess intensity; the composition of crystalline formationsis determined, while, simultaneously, establishing theconstitution of urate salts in the central zone of that sameurine sample, followed by carrying out a comparative analysisto said two compositions to determine the composition oflithogenic urate salts.