METHOD FOR THE ISOLATION AND/OR ASSAY OF DAMAGED DNA AND ITS APPLICATION TO SCREENING OF CYTOTOXIC PRODUCTS ACTING ON DNA

摘要

The invention concerns a method for the isolation and/or assay of damaged DNA in a sample, characterised in that it consists in assessing the importance of the fixation of TBP or of an analogous product on the DNA sample and in determining the results directly or relative to a control. This method can be used for screening cytotoxic products acting on DNA.