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Lubricant compositions that are spreadable onto and adherable to biomembranes, method of making and use thereof

机译:可涂在生物膜上并粘附在生物膜上的润滑剂组合物,其制备方法和用途

摘要

This invention relates to compositions that are easily spreadable onto and adhesive to biomembranes. They contain and provide moisture to the biomembranes and do not readily flow off, i.e., leak from, the biomembranes. Nor are they readily removed or washed from the biomembranes. Compositions that adhere to and are compatible with, in that they spread, and do not flow off and are not readily removed or washed from the biomembranes are deemed to be bioadhesive. Such compositions are particularly useful for maintaining biomembranes in a moist condition, for lubricating the biomembranes, and for providing a vehicle for containing and delivering medicaments, such as contraceptives, antifungals and antibacterials. The invention further relates to methods for making and methods of use of such compositions.The compositions of this invention are particularly useful for maintaining biomembranes in a moist condition, especially those that are susceptible to dryness, for lubricating the biomembranes and for providing a vehicle for containing and delivering medicaments, such as contraceptives, antifungals and antibacterials.
机译:本发明涉及易于在生物膜上铺展并粘附于生物膜的组合物。它们含有生物膜并为生物膜提供水分,并且不容易从生物膜中流出,即从生物膜泄漏。它们也不容易从生物膜中去除或清洗。粘附并与其相容的组合物,因为它们铺展,不脱落,不容易从生物膜上除去或洗涤,被认为是生物粘附的。此类组合物对于将生物膜保持在湿润状态,润滑生物膜以及提供用于容纳和递送药物(例如避孕药,抗真菌药和抗菌剂)的载体特别有用。本发明进一步涉及这种组合物的制备方法和使用方法。本发明的组合物特别可用于将生物膜保持在湿润状态,特别是对干燥敏感的生物膜,润滑生物膜并提供用于容纳和输送药物如避孕药,抗真菌药和抗菌药的载体。

著录项

  • 公开/公告号EP0818194A2

    专利类型

  • 公开/公告日1998-01-14

    原文格式PDF

  • 申请/专利权人 MCNEIL-PPC INC.;

    申请/专利号EP19970109783

  • 发明设计人 SCHIRALDI MICHAEL T.;BURNETT KATHERINE M.;

    申请日1997-06-16

  • 分类号A61K9/08;

  • 国家 EP

  • 入库时间 2022-08-22 02:49:52

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