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19-FLUORO OR CYANO-21-HYDROXYPROGESTERONE DERIVATIVES USEFUL AS 19-HYDROXYLASE INHIBITORS
19-FLUORO OR CYANO-21-HYDROXYPROGESTERONE DERIVATIVES USEFUL AS 19-HYDROXYLASE INHIBITORS
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机译:19-氟或氰基-21-羟孕酮衍生物可用作19-羟化酶抑制剂
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摘要
19-Fluoro- and cyano- substituted 21-hydroxyprogesterone derivatives and related compounds which are active as 19-hydroxylase inhibitors and useful as antihypertensive agents are described herein. The compounds are prepared using appropriate synthetic pathways which will vary according to the nature of the specific 19-substituted progesterone or related compound desired.
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