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Antiepileptic drugs similar to valproic acid
Antiepileptic drugs similar to valproic acid
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机译:类似于丙戊酸的抗癫痫药
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摘要
The invention provides compounds which are effective antiepileptics and at the same time display only a slight sedative and teratogenic effect and have the formula IMAGE (I) IMAGE (II) IMAGE (III) IMAGE (IV) where the compounds of the formulae (I) and (II) can also be mono- or polyunsaturated, in which R1, R2, R3 and R4 are each, independently of one another, hydrogen or a C1-C6-alkyl group, R5 is hydrogen or a C1-C2-alkyl group, and at least one of the radicals R1 to R4 in the compounds of the formulae (I) and (II) is different from hydrogen, where the compounds of the formula (I), in the case where a center of asymmetry is present on the carbon atom in position 2, and the compounds of the formulae (II), (III) and (IV) are in the form of their racemate, their pure enantiomers or a mixture of their enantiomers which differs from the racemate, and pharmaceutically compatible salts thereof.
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