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Process of preparation of a medicinal product containing plasma protein and medicine containing plasma protein
Process of preparation of a medicinal product containing plasma protein and medicine containing plasma protein
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机译:含有血浆蛋白的药物产品和含有血浆蛋白的药物的制备方法
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摘要
There is disclosed a method of preparing a plasma-protein-containing medicament from citrated plasma or from a citrate-containing plasma fraction, the medicament being substantially free from undesired metals, which method comprises the following steps: exchanging the citrate and optionally citrate-bound metals in a plasma-protein-containing solution for a water-soluble mono- or dicarboxylate or for an organic mono- or dicarboxylic acid under non-precipitating conditions, recovering the plasma protein or the plasma proteins, and finishing the medicament.
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