Backbone cyclic peptide fragments and their analogs derived from pban 1-33, useful as insecticides

摘要

Backbone cyclic peptides consisting of fragments derived from the amino acid sequence of Pheromone Biosynthesis Activating Neuropeptide (PBAN) and their analogs are disclosed. These backbone cyclic peptides are useful as insecticides. Moreover, conformational libraries thereof are disclosed to be useful as a basis for the design of improved antagonist insecticides and for the discovery of insecticides. A method for controlling insects, preferably moths, utilizing said backbone cyclic peptide fragments and analogs derived from the PBAN sequence is also disclosed.