Dictyocaulus viviparus antigen for diagnosing lungworm infestation and for vaccination

摘要

An immunogenic protein, called DV18, isolated from adult lungworms of the species Dictyocaulis viviparus is new. Also claimed are: (1) DNA encoding DV18; and (2) recombinant DV18 having a partial amino acid sequences as shown below: TPPAGVFYQGXSATPIA; The N-terminal of these sequences can be joined to D, N, S, G or R: XLGVDPASGVLDPKEATLMA; NLPIEYNP; AFRREWFQGDG(M)VRRK; DVFNAPYDDK; XPPAGVFYQWSATPIANGSLG; THYIK (The N-terminal of this peptide can be joined to D, S, G or A); and IINASGRRIGWAIK (The N-terminal of this peptide can be joined to D or H).