BORDETELLA PERTUSSIS ANTIGENS AS CARRIERS IN VACCINATING CONJUGATES AND ORAL VACCINES COMPRISING BORDETELLA PERTUSSIS FIMBRIAE

摘要

A vaccinating conjugate comprises an antigen conjugated to a carrier selected from Bordetella pertussis fimbria, pertussis toxin, pertussis toxoid, and pertussis 69kD protein. The conjugate may also comprise a second antigen, different from the first. An oral vaccinating composition comprises Bordetella pertussis fimbria or fimbria-antigen conjugate.