;On account of the presence of the asymmetrical atom of carbon, indicated by the asterisk, the compound (I) exists in two isomeric forms, one dextrorotatory and the other levorotatory.;Described herein is the levorotatory enantiomer L(-) cloperastine and its salts (e.g., hydrochloride - fendizoate) which has made it possible to obtain a more active, less toxic product having fewer side effects compared to the D(+) isomer and the racemic mixture currently available on the market.;In the clinical field, this means a better tolerability and safety of use of the drug."/>
Optical isomers of cloperastine
The present invention regards the optical isomers of cloperastine, a compound having the following formula:;On account of the presence of the asymmetrical atom of carbon, indicated by the asterisk, the compound (I) exists in two isomeric forms, one dextrorotatory and the other levorotatory.;Described herein is the levorotatory enantiomer L(-) cloperastine and its salts (e.g., hydrochloride - fendizoate) which has made it possible to obtain a more active, less toxic product having fewer side effects compared to the D(+) isomer and the racemic mixture currently available on the market.;In the clinical field, this means a better tolerability and safety of use of the drug.
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机译：本发明涉及氯吡斯汀的旋光异构体，其具有下式： <图像文件=“ IMGA0001.GIF” he =“ 33” id =“ ia01” imgContent =“ chem” imgFormat =“ GIF” wi =“ 106” /> ;开考虑到星号指示的碳的不对称原子的存在，化合物（I）以两种异构体形式存在，一种是右旋的，另一种是左旋的。;本文描述的是左旋对映异构体L（-）氯萘斯汀及其盐（与目前市场上可买到的D（+）异构体和外消旋混合物相比，它能获得具有更少副作用的更活泼，毒性更小的产品。药物的耐受性和安全性更高。
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