PROCESS FOR CROSS-LINKING OF COLLAGEN BY DIPHENYLPHOSPHORYLAZIDE, THE CROSSLINKED COLLAGEN OBTAINED THEREBY AND COLLAGEN BASED BIOMATERIALS CROSS-LINKED

摘要

The present invention relates to a method for producing cross-linked collagen.;The method is a method of the form consisting of the formation of amide bonds by acyl azide groups and the reaction of collagen with diphenylphosphoryl azide groups.;The method according to the invention simplifies the collagen crosslinking method and can control the degree of crosslinking upon separation without the introduction of any crosslinking agent.