Method for preparing glycosaminoglycans having heparin or heparan structure with α-L-iduronic-2-0-sulfate acid modified in 2-position

摘要

The present invention relates to the following general formula (III) having a heparin or heparan structure in which the 2-position of α-L-iduronic-2-0-sulfate in which the sulfate group is substituted in whole or in part by nucleophilic radicals It relates to a method for producing synthetic glycosaminoglycans.;The preparation method is carried out by treating a glycosaminoglycan having a heparin or heparan structure with a nucleophilic reagent in an alkaline medium.