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Human neuronal nicotinic acetylcholine receptor and cells transformed with same DNA and mRNA encoding an--subunit of
Human neuronal nicotinic acetylcholine receptor and cells transformed with same DNA and mRNA encoding an--subunit of
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机译:人神经元烟碱型乙酰胆碱受体和编码相同亚基的亚基的相同DNA和mRNA转化的细胞
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摘要
DNA encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing said DNA, methods for producing alpha and beta subunits and recombinant (i.e., isolated or substantially pure) alpha subunits (specifically &agr;.sub. 4 and . alpha..sub.7) and beta subunits (specifically &bgr;.sub.4) are provided. In addition, combinations of subunits (i.e., &agr;.sub.1, . alpha..sub. 2, &agr;.sub.3, &agr;.sub.4, and/or &agr;.sub.7 subunits in combination with &bgr;.sub.4 subunits; or &bgr;.sub.2, . beta..sub.3 and/or &bgr;.sub.4 subunits in combination with &agr;.sub. 4 and/or . beta..sub.7 subunits) are provided.
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