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Transgenic mice as a model for metabolic bone diseases
Transgenic mice as a model for metabolic bone diseases
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机译:转基因小鼠作为代谢性骨疾病的模型
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摘要
Transgenic mice carrying a recombinant DNA construct comprising the gene encoding diphtheria toxin A chain operably linked to a osteocalcin promoter. The transgenic mice can be used as a model for metabolic bone diseases since they have decreased bone mass associated with a marked reduction in the number of osteoblasts.
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