The method of manufacturing the intermediate field for synthesis of the anti- true germ medicine

摘要

(57) Abstract The method of producing crystal characteristic kiraruhidorokishiesuteru of formula (1.0) is disclosed. This method includes in the acetonitrile of the effective quantity, the fact that it reacts with the diol of formula (2.0) and the anhydrous iso butyric acid of the effective quantity and the lipase enzyme of the effective quantity, the said reaction is done in low temperature, here, X¹ and X², becoming independent respectively, is selected from F or Cl: