Method for the detection of antibodies to a 230 kd antigen present in leishmania chagasi and leishmania donovani; kit; isolated dna; 230 kd antigen isolated; and vaccine composition

摘要

A method for detecting anti-Leishmania parasite antibodies to a 230 kDa antigen present in Leishmania chagasi and Leishmania donovani is disclosed which comprises obtaining a sample from an individual, contacting the sample with a recombinant K39 repeat unit antigen comprising the amino acid sequence as shown in SEQ ID NO:3, and detecting the presence of anti-Leishmania parasite antibodies in the sample which bind to the recombinant K39 repeat unit antigen.