首页> 外国专利> Processes for preventing a cytotoxic amyloid beta protein in cells, treating a fibrilogen in a human subject, decreasing oxidation in a biological sample and treating diseases or other conditions in which free radicals and / or oxidative stress play a role role, and, use of indole-3-propionic acid or a salt or ester thereof.

Processes for preventing a cytotoxic amyloid beta protein in cells, treating a fibrilogen in a human subject, decreasing oxidation in a biological sample and treating diseases or other conditions in which free radicals and / or oxidative stress play a role role, and, use of indole-3-propionic acid or a salt or ester thereof.

机译:预防细胞中细胞毒性淀粉样β蛋白,在人类受试者中治疗纤维蛋白原,降低生物样品中的氧化以及治疗其中自由基和/或氧化应激起重要作用的疾病或其他病症的方法,以及吲哚的用途-3-丙酸或其盐或酯。

摘要

'' PROCESSES FOR THE PREVENTION OF A CYTOTHOXIC EFFECT OF AMILOID BETA PROTEIN IN CELLS, FOR THE TREATMENT OF A FIBRYLOGENIC DISEASE IN A HUMAN SUBJECT, FOR THE DECREASE OF OXIDATION IN A BIOLOGICAL SAMPLE AND A TREATMENT OF TREATMENT IN ORAL TREATMENT AND / OR TREATMENT. OXIDATIVE TENSION PLAY A ROLE, AND USE OF INDOL-3-PROPYNIC ACID OR ITS SALT OR ESTER '' The cytotoxic effects of amyloid beta protein in cells are prevented by contacting cells with an effective amount of indole-3 acid -propionic or its salt or ester. In addition, a fibrilogenic disease can be treated in a human subject by administering to the human subject an amount of an indole-3-propionic acid or a salt or ester thereof that is effective in preventing or reversing fibrillogenesis. Oxidation in a biological sample can be reduced by contacting the biological sample with an effective amount of an indole-3-propionic acid or a salt or ester thereof. In addition, diseases or other conditions in which free radicals and / or oxidative stress play a role can be treated by administering an effective amount of an indole-3-propionic acid or a salt or ester thereof.
机译:''预防细胞中的拟南芥贝塔蛋白的细胞毒作用,治疗人类纤维化疾病,减少生物样品中的氧化以及治疗/口腔治疗的方法。氧化张力发挥作用,以及使用吲哚3-丙酸或其盐或酯''通过使细胞与有效量的吲哚3酸-丙酸或其盐接触,可防止淀粉样β蛋白对细胞的细胞毒性作用或酯。另外,可以通过向人对象施用有效预防或逆转原纤维形成的吲哚-3-丙酸或其盐或酯的量来治疗人对象的原纤维形成性疾病。通过使生物样品与有效量的吲哚-3-丙酸或其盐或酯接触,可以减少生物样品中的氧化。另外,可以通过施用有效量的吲哚-3-丙酸或其盐或酯来治疗其中自由基和/或氧化应激起作用的疾病或其他病症。

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