ANGIOTENSIN II ANTAGONISTS AS PROFILACTIC OR THERAPEUTIC DRUGS FOR RENAISSANCE DISEASES

摘要

This invention relates to prophylactic or therapeutic drug for diabetic nephropathy or glomerulonephritis, comprising, as an active ingredient, a compound or salt thereof represented by general formula (I) CHEM wherein R1 stands for H or an optionally substituted hydrocarbon residue; R2 stands for an optionally esterified carboxyl group; R3 stands for a group actually or potentially capable of forming an anion; X shows that the phenylene and phenyl groups bind to each other directly or through a spacer having an atomic chain length of two or less; n stands for 1 or 2; ring A stands for a benzene ring having an optional substituent in addition to R2; Y stands for a bond, -O-, -S(O)m- (wherein m stands for 0, 1 or 2), or -N(R4)- (wherein R4 stands for H or an optionally substituted alkyl group).