ORAL PREPARATIONS CONTAINING FORSKOLIN DERIVATIVES AND PROCESS FOR PRODUCING MEDICINAL PREPARATIONS

摘要

Oral preparations excellent in storage stability and containing salts offorskolin derivatives represented by general formula (1), such as colforsindapropate hydrochloride [6-(3-dimethylaminopropionyl)forskolin], and alkalimetal halides wherein R1 represents hydrogen; R4 represents vinyl; and one ofR2 and R3 represents -CO(CH2)mNR5R6 (wherein R5 and R6 represent each loweralkyl, etc. and m is an integer of from 1 to 5), while another representshydrogen or -CO(CH2)nX [wherein X represents hydrogen or -NR7R8 (wherein R7and R8 represent each lower alkyl, etc.), and n is an integer of from 1 to 5].