NEW CRYSTALLINE MODIFICATION OF 5-FLUORO-1-(TETRAHYDRO-2-FURYL)-URACYL, AND COMPLEX COMPOUNDS BASED ON THIS MODIFICATION AND HAVING AN ANTITUMORAL ACTIVITY

摘要

The present invention relates to a new polymorphous and previously unknown modification of 5-fluoro-1-(tetrahydro-2-furyl)-uracyl which exhibits an antitumoral activity. This form is crystalline, substantially differs from the known ones due to its characteristics and essentially has an increased specific activity. This new form is physically stable and can be used in medicine for treating patients affected by tumours. This invention also relates to new anticancer drug substances which are obtained from this modification in the form of stable molecular complexes, mainly crystalline complexes comprising 6-methyluracyl and amorphous complexes comprising biologically active substances from an extract of liquorice roots.