50, not less, suspension of adsorbed inactivated culture of parvovirus strain "Gerkules" in carnivore animals, 6log2 HAU, not less (before inactivation), inactivated viral suspension of the strain Mammaliadenovirus adenovirus canis 2"Ada", 4 lg TCD50, not less, and mixed suspension of leptospira of serogroups Canicola VGNKI-3 and Icterohaemorrhagiae VGNKI-2 taken in the equal ratio of bacterial cells, 200-400 mln cells per dose. EFFECT: high immunogenicity and thermostability of mixed vaccine during prolonged storage. 1 ex"/>
VACCINE 'BIOVAK' AGAINST PLAGUE IN CARNIVORE ANIMALS, PARVOVIRAL ENTERITIS, INFECTIOUS HEPATITIS, ADENOVIROSIS AND LEPTOSPIROSIS IN DOGS
FIELD: veterinary science, microbiology. SUBSTANCE: invention relates to agents used for specific prophylaxis of diseases in dogs. Mixed vaccine "Biovak" has (per a single vaccine dose 2 ml) dried virus-containing liquid of the plague virus strain ЭПММ in carnivore animals and stabilizing agent, titer is 2.2 lg TCD50, not less, suspension of adsorbed inactivated culture of parvovirus strain "Gerkules" in carnivore animals, 6log2 HAU, not less (before inactivation), inactivated viral suspension of the strain Mammaliadenovirus adenovirus canis 2"Ada", 4 lg TCD50, not less, and mixed suspension of leptospira of serogroups Canicola VGNKI-3 and Icterohaemorrhagiae VGNKI-2 taken in the equal ratio of bacterial cells, 200-400 mln cells per dose. EFFECT: high immunogenicity and thermostability of mixed vaccine during prolonged storage. 1 ex
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机译：领域：兽医学，微生物学。物质：本发明涉及用于特异性预防狗疾病的药剂。混合疫苗“ Biovak”在食肉动物和稳定剂中具有（每剂2毫升单剂量）干燥的鼠疫病毒株ЭПММ的含病毒干燥液和稳定剂，滴度为2.2 lg TCD 50 ，不少于细小病毒“ Gerkules”毒株在食肉动物中的6log 2 HAU吸附灭活培养物的悬浮液，不少于（灭活前），犬乳腺病毒腺病毒canis 2“ Ada”，4 lg TCD灭活病毒悬浮液 50 （不少于），血清群Canicola VGNKI-3和Ictero haemorrhagiae VGNKI-2的钩端螺旋体的混悬液以相等比例的细菌细胞摄取，每剂量200-400百万个细胞。效果：长时间存放期间混合疫苗具有很高的免疫原性和热稳定性。 1前
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